Safety and efficacy of Elisrasib (D3S-001), a next generation GDP-bound KRAS G12C inhibitor, as monotherapy in advanced non-small cell lung cancer (NSCLC) previously treated with or without a KRAS G12C inhibitor: Results from a phase 1/2 study 会议名称:Clinical Trials Plenary 1: New Frontiers in Precision Oncology 时间:2026年4月19日(周日)13:00–15:00 报告编号:CT020 该研究将以口头报告形式在临床试验全体大会上展示。
Safety and efficacy of Elisrasib (D3S-001), a next generation GDP-bound KRAS G12C inhibitor, as monotherapy or combination therapy with cetuximab in previously treated metastatic CRC and PDAC: Results from a phase 1/2 study 会议名称:Advances in Precision Oncology 时间:2026年4月21日(周二)14:30–16:30 报告编号:CT303 该研究将以口头报告形式在临床试验专题研讨会上展示。
海报展示详情如下:
First in human phase 1 study of D3S-002, a purposely designed ERK1/2 inhibitor, in advanced solid tumors with MAPK pathway mutations 会议名称:First-in-Human Phase I Clinical Trials 时间:2026年4月20日(周一)9:00–12:00 展区:Poster Section 50 展板编号:20 摘要编号:CT060
First-in-human clinical pharmacokinetic prediction of D3S-003, an orally bioavailable dual-state KRAS G12D inhibitor 会议类别:Experimental and Molecular Therapeutics 会议名称:Quantitative Pharmacology and Translational Modeling 时间:2026年4月20日(周一)9:00–12:00 展区:Poster Section 17 展板编号:19 摘要编号:1831
D3S-003, an orally bioavailable potent and selective dual-state inhibitor targeting both GDP- and GTP-bound KRAS G12D 会议类别:Experimental and Molecular Therapeutics 会议名称:Novel Antitumor Agents 2 时间:2026年4月21日(周二)9:00–12:00 展区:Poster Section 17 展板编号:12 摘要编号:4569